Inflammatory markers in rheumatic diseases

Immune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading inflammation and irreversible organ damage. Laboratory diagnosis IMRDs includes wide range biomarkers (autoantibodies, acute phase proteins, cytokines, markers endothelial damage, components the complement system, immunoglobulins, cryoglobulins, lymphocyte subpopulations, indicators bone metabolism, apoptosis markers, genetic etc). One aspects laboratory is study level in blood (erythrocyte sedimentation rate, C-reactive protein (CRP), serum amyloid (CAA), ferritin, procalcitonin, apolipoprotein AI, calprotectin, The analysis makes it possible assess disease activity, nature progression prognosis outcomes chronic inflammatory process, as well effectiveness therapy. review presents latest data role most frequently studied such CRP, CAA ferritin.